PrediSi
PREDIction of SIgnal peptides
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Literature:

  • von Heijne, G. (1985) Signal sequences. The limits of variation. Journal of molecular biology 184 , 99-105 [PUBMED]

  • Rapoport, TA., Jungnickel, B. & Kutay, U. (1996) Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annu. Rev. Biochem. 61, 271-303 [PUBMED]

  • Nielsen, H., Engelbrecht, J., Brunak, S. & von Heijne, G. (1997) Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1-6 [PUBMED]

  • Zheng, N. and Gierasch, L..M. (1996) Signal sequences: the same yet different. Cell 86, 849-852 [PUBMED]

  • Rapoport T.A., Jungnickel B. and Kutay U. (1996) Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annual review of biochemistry 65, 271-303 [PUBMED]

  • Nielsen, H., Engelbrecht, J., von Heijne, G. and Brunak, S. (1996) Defining a Similarity Threshold for a Functional Protein Sequence Pattern: The Signal Peptide Cleavage Site. Proteins 24 , 165-177 [PUBMED]

  • Menne, K. M. L., Hermjakob, H. and Apweiler, R. (2000) A comparison of signal sequence prediction methods using a test set of signal peptides. Bioinformatics 16, 741-742 [PUBMED]

  • Schreiber M. and Brown C. (2002) Compensation for nucleotide bias in a genome by representation as a discrete channel with noise. Bioinformatics 18 , 507-512 [PUBMED]

  • Boeckmann B., Bairoch A., Apweiler R., Blatter M.-C., Estreicher A., Gasteiger E., Martin M.J., Michoud K., O'Donovan C., Phan I., Pilbout S. and Schneider M. (2003) The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. Nucleic Acids Research. 31, 365- 370 [PUBMED]

  • Hiller, K., Schobert, M., Hundertmark, C., Jahn, D. & Münch, R. (2003) JVirGel: calculation of virtual two-dimensional protein gels. Nucleic Acids Res. 31, 3862-3865 [PUBMED]
 
Other bioinformatic tools from our team:

JVirGel - Virtual 2D-protein gels

PRODORIC - Prokaryotic Database of Gene Regulation and Regulatory Networks

 © 2003 by Karsten Hiller •  Institute for Microbiology •  Technical University of Braunschweig •  contact: karsten.hiller@tu-braunschweig.de